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Window Layout — this option allows to control the behavior of windows, multiple or tabs.

Preferred Web browser — you can use either System default browser or specify some other browser.

Open last project at startup — if the option is checked, the last project is opened when UGENE is started. Also you can choose default settings for saving project.

Enable statistical reports collecting — collects information about UGENE usage and sends it to the UGENE team to help improve the application.

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