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- Download the zip archive for your platform (32-bit or 64-bit). Choose Standard, Full, or NGS package (the NGS package is available for 64-bit platform only).
- Unpack the archive.
- Open the unpacked folder and run "ugeneui.exe" (i.e. UGENE User Interface).
On a new UGENE version release, a notification will appear. However, to install the new version, it is required to manually download the package again.