Imagine that you have browsed for required data (e.g. a sequence with annotations) and opened, for example, an html view for the data in a web browser. Now you would like to open the data in UGENE to analyze them in more detail. Or, alternatively, maybe you would like to analyze a certain sequence part.
In this case you select the required data in the web browser window. the Open selected in UGENE item should now appear in the context menu:
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<img src="/wiki/download/attachments/4227834/Opening selected data in UGENE.png"/>
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The selected data will be opened in UGENE.