T-Coffee is a multiple sequence alignment package.
T-Coffee home page: T-Coffee
To make T-Coffee available from UGENE see the External Tools.
To use T-Coffee open a multiple sequence alignment file and select the Align with T-Coffee item in the context menu or in the Actions main menu. The following dialog appears:
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<center> <br> <img src="/wiki/download/attachments/4228545/T-Coffee.png"/> <br> </center> |
The following parameters are available:
Gap opening penalty — indicates the penalty applied for opening a gap. The penalty must be negative.
Gap extension penalty — indicates the penalty applied for extending a gap.
Number of iterations — specifies the number of iterations.