Searches each input sequence for transcription factor binding sites significantly similar to specified SITECON profiles. In case several profiles were supplied, searches with all profiles one by one and outputs merged set of annotations for each sequence.
Element type: sitecon-search
Parameters
| Parameter | Description | Default value | Parameter in Workflow File | Type |
|---|---|---|---|---|
| Result annotation | Name of the result annotations. | misc_feature | result-name | string |
| Search in | Specifies which strands should be searched: direct, complement or both. | both strands | strand | numeric Available values are:
|
| Min score | Recognition quality threshold, should be less than 100%. Choosing too low threshold will lead to recognition of too many TFBS recognised with too low trustworthiness. Choosing too high threshold may result in no TFBS recognised. | 85 | min-score | numeric |
| Min err1 | Alternative setting for filtering results, minimal value of Error type I. Note that all thresholds (by score, by err1 and by err2) are applied when filtering results. | 0.0 | err1 | numeric |
| Max err2 | Alternative setting for filtering results, max value of Error type II. Note that all thresholds (by score, by err1 and by err2) are applied when filtering results. | 0.001 | err2 | numeric |
Input/Output Ports
The element has 2 input ports. The first port:
Name in GUI: Sequence
Name in Workflow File: in-sequence
Slots:
| Slot In GUI | Slot in Workflow File | Type |
|---|---|---|
| Sequence | sequence | sequence |
The second input port gets the SITECON model:
Name in GUI: Sitecon model
Name in Workflow File: in-sitecon
Slots:
| Slot In GUI | Slot in Workflow File | Type |
|---|---|---|
| Sitecon model | sitecon-model | sitecon-model |
And there is 1 output port:
Name in GUI: Sitecon annotations
Name in Workflow File: out-annotations
Slots:
| Slot In GUI | Slot in Workflow File | Type |
|---|---|---|
| Set of annotations | annotations | annotation-table |